Thermo Fisher Scientific DGAT2 Polyclonal Antibody
DGAT2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 최적화됨. E. coli 유래 인간 DGAT2 단편을 면역원으로 사용. 비결합형, 액상 형태, 1 mg/mL 농도. 지방산 대사 연구용으로 적합.
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Thermo Fisher Scientific DGAT2 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human DGAT2 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2866929 |
Target Information
Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, suggesting its important role in mammalian triglyceride metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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