Thermo Fisher Scientific SOCS3 Monoclonal Antibody (OTI6C12), TrueMAB
Human SOCS3 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot과 Immunocytochemistry에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 안정적인 저장 버퍼를 포함합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6C12 |
| Immunogen | Full length human recombinant protein of human SOCS3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.46 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokine receptor signaling is negatively regulated by a family of Src homology 2 domain-containing adaptor molecules termed SOCS (Suppressor of Cytokine Signaling). There are eight members of the SOCS family: SOCS-1, SOCS-2, SOCS-3, SOCS-4, SOCS-5, SOCS-6, SOCS-7, and CIS. Structurally, SOCS proteins consist of a variable N-terminal region, a central SH2 domain, and a C-terminal SOCS box motif. They function as part of a negative feedback loop that regulates cytokine signal transduction via STAT-induced transcriptional mechanisms. Transcription of SOCS genes occurs rapidly in response to cytokines, and SOCS proteins inhibit signaling in various ways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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