Thermo Fisher Scientific C1QA/Complement C1q A-Chain Monoclonal Antibody (C1QA/2954)
인간 C1QA 단백질을 인식하는 단클론 항체로, Western blot 및 면역조직화학(IHC)에 적합. 마우스 IgG2b, kappa 아이소타입이며 비결합형 액상 형태. 단백질 A/G로 정제되었으며 PBS 완충액에 보존. 루푸스 및 사구체신염 관련 연구에 유용.
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Thermo Fisher Scientific C1QA/Complement C1q A-Chain Monoclonal Antibody (C1QA/2954)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C1QA/2954 |
| Immunogen | Recombinant fragment (around aa 104–237) of human C1QA protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
C1q is a sub-component of complement C1. It associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade.
Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis.
C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region near the N terminus and a C-terminal globular region.
The A-, B-, and C-chains are arranged in the order A–C–B on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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