Thermo Fisher Scientific PRPH2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PRPH2. Recombinant protein control fragment (Product #RP-91075). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PRPH2,uniProtId:P23942-1,ncbiNodeId:9606,antigenRange:124-248,antigenLength:346,antigenImageFileName:PA5-56154_PRPH2_P23942-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56154_PRPH2_P23942-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.10 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645979

Product Specific Information

Immunogen sequence: GSLENTLGQG LKNGMKYYRD TDTPGRCFMK KTIDMLQIEF KCCGNNGFRD WFEIQWISNR YLDFSSKEVK DRIKSNVDGR YLVDGVPFSC CNPSSPRPCI QYQITNNSAH YSYDHQTEEL NLWVR

Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 50%.

Target Information

Peripherin-2 (PRPH2), also known as retinal degeneration slow protein (RDS), is a photoreceptor-specific tetraspanin protein implicated in outer segment disk morphogenesis. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Mutations in peripherin-2 are responsible for various retinal degenerative diseases including autosomal dominant retinitis pigmentosa (ADRP).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.