Thermo Fisher Scientific XTP4 Monoclonal Antibody (OTI2D2)
XTP4 단백질을 인식하는 OTI2D2 클론 단일클론 항체로, 인간·마우스·래트 등 다양한 종에서 반응합니다. Western blot, IHC, Flow Cytometry에 사용 가능하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Non-human primate, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D2 |
| Immunogen | Full length human recombinant protein of C17orf37 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723791 |
Target Information
During the past decade, the role of the ERBB2 (neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established.
The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies.
The C35 gene is located on chromosome 17q12, 505 nucleotides from the 3' end of the ERBB2 oncogene, the antigenic target for trastuzumab (Herceptin) therapy.
The chromosomal arrangement of the genes encoding C35 and ERBB2 is tail to tail.
The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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