Thermo Fisher Scientific ANKK1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ANKK1. Recombinant protein control fragment (Product #RP-89809). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ANKK1,uniProtId:Q8NFD2-1,ncbiNodeId:9606,antigenRange:319-459,antigenLength:765,antigenImageFileName:PA5-52987_ANKK1_Q8NFD2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52987_ANKK1_Q8NFD2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637949

Product Specific Information

Immunogen sequence: EVNEDISQEL MDSDSGNYLK RALQLSDRKN LVPRDEELCI YENKVTPLHF LVAQGSVEQV RLLLAHEVDV DCQTASGYTP LLIAAQDQQP DLCALLLAHG ADANRVDEDG WAPLHFAAQN GDDGTARLLL DHGACVDAQE R

Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 77%.

Target Information

ANKK1 serine/threonine kinase is a member of the RIPK family and is closely linked to the DRD2 gene. ANKK1 is closely linked to DRD2 gene on chr 11, and a well studied restriction fragment length polymorphism designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene, where it causes a nonconservative amino acid substitution. It is not clear if ANKK1 plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.