Thermo Fisher Scientific CYP1B1 Polyclonal Antibody
Rat CYP1B1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 합성 펩타이드(C-terminal region)로 면역화되었으며, 0.5 mg/mL 농도의 액상 형태입니다. 약물 대사 및 안구 발달 관련 연구에 활용 가능합니다.
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Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of rat CYP1B1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691354 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Target Information
CYP1B1 is a 543 amino acid intracellular protein localized to the endoplasmic reticulum. It belongs to the cytochrome P450 superfamily of enzymes (monooxygenases) and catalyzes reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. This enzyme metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17β-estradiol, and is involved in the metabolism of substances active in eye growth and differentiation, playing a potential role in ocular development. Mutations in this protein are associated with primary congenital glaucoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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