Thermo Fisher Scientific RNF19A Polyclonal Antibody
RNF19A 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 인간 및 생쥐 시료에 반응하며, Affinity chromatography로 정제됨. PBS 및 50% glycerol buffer에 보관되며, 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RNF19A (Accession Q9NV58), corresponding to amino acid residues S52–C102 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852614 |
Product Specific Information
Antibody detects endogenous levels of total RNF19A.
Target Information
This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in-between RING fingers motif.
This protein is an E3 ubiquitin ligase localized to Lewy bodies and ubiquitylates synphilin-1, an interacting protein of alpha-synuclein in neurons.
The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson’s disease.
Alternative splicing results in multiple transcript variants.
[Provided by RefSeq, Jul 2013].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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