
Thermo Fisher Scientific ACMSD Polyclonal Antibody
ACMSD 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot 및 IHC(P)에서 검증되었으며, 인간과 마우스에 반응합니다. 항원 친화 크로마토그래피로 정제되었고, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 105–336 of ACMSD (Uniprot ID: Q8TDX5) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.86 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11155616 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, Molt-4, Raji, mouse brain
- Predicted reactivity: Mouse (91%), Rat (89%), Zebrafish (87%), Bovine (93%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan and has been implicated in several neurodegenerative disorders.
Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS).
ACMSD (ACMS decarboxylase; EC 4.1.1.45) diverts ACMS to a benign catabolite, preventing quinolinate accumulation.
(Information supplied by OMIM, Oct 2004)
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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