Thermo Fisher Scientific SESTD1 Monoclonal Antibody (OTI2E7), TrueMAB
SESTD1 단백질을 표적으로 하는 Mouse IgG1 단클론 항체. Western blot, IHC, ICC/IF에 사용 가능. 고순도 친화 크로마토그래피 정제 및 동결건조 형태. 인간 및 마우스 반응성. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E7 |
| Immunogen | Full length human recombinant protein of human SESTD1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting kit: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
SESTD1 was first identified in mutant zebrafish with spontaneous contraction and touch response defects as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains.
SESTD1 interacts with TRPC4 and TRPC5, members of the transient receptor potential channel family, through the TRPC calmodulin- and inositol 1,4,5-triphosphate receptor-binding domain, and is essential for efficient receptor-mediated activation of TRPC5.
These findings suggest that SESTD1 is a novel regulator of TRPC proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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