Thermo Fisher Scientific FPR2/ALX (extracellular) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200

-

Flow Cytometry (Flow)

2.5 µg

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

(C)GGTPEERLKVAIT, corresponding to amino acid residues 184-196 of human FPR2/ALX, 2nd extracellular loop if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FPR2,uniProtId:P25090-1,ncbiNodeId:9606,antigenRange:184-196,antigenLength:351,antigenImageFileName:AFR-002-200UL_FPR2_P25090-1_Rabbit.svg,antigenImageFileNamePDP:AFR-002-200UL_FPR2_P25090-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.6 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 1% BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).

Target Information

Formyl peptide receptor 2 (FPR2) is a low affinity receptor for N-formyl-methionyl peptides. Binding of FMLP to FPR2 causes activation of neutrophils. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.