Thermo Fisher Scientific ABCF2 Polyclonal Antibody
ABCF2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB, IHC(P), ICC/IF에 사용 가능. 고순도 항원 친화 크로마토그래피 정제 및 PBS 기반 완충액에 보존. 인체, 마우스, 랫트 반응성.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ABCF2. Recombinant protein control fragment (Product #RP-92613). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2637536 |
Product Specific Information
Immunogen sequence:
KEAAKARQRP RKGHEENGDV VTEPQVAEKN EANGRETTEV DLLTKELEDF EMKKAAARAV TGVLASHPNS TDVHIINLSL TFHGQELLSD TKLELNSGRR YGLIGLNGIG KS
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 97%
Target Information
OCIAD1 was identified via immunoscreening of an ovarian carcinoma cDNA library from ovarian cancer patients and is expressed in multiple tissues including ovary, placenta, brain, testis, prostate, and mammary gland. Two isoforms of OCIAD1 are known to exist; the shorter isoform is restricted to the central nervous system. OCIAD1 is a transmembrane protein whose overexpression in HEY ovarian cancer cells increased lysophosphatidic acid (LPA)-induced, but not basal level cell adhesion to extracellular matrix proteins collagen I and laminin10/11. This adhesion is not blocked by LY294002 and GF109203X, suggesting that OCIAD1 does not use protein kinase C and PI3 kinase signaling pathways to exert its effect on adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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