Thermo Fisher Scientific ABCC5 Monoclonal Antibody (OTI1F3), TrueMAB
ABCC5 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화됨. 인간 시료 반응성. Affinity chromatography로 정제된 액상형 항체이며, PBS/BSA/glycerol 용액에 보존. 약물 내성 및 ABC 수송체 연구에 유용.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F3 |
| Immunogen | Full length human recombinant protein of human ABCC5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily, which mediates the transport of various molecules across cellular membranes. ABC genes are categorized into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
ABCC5 (MRP5) is part of the MRP subfamily involved in multidrug resistance and functions in the cellular export of cyclic nucleotides. This export contributes to phosphodiesterase degradation and may serve as a pathway for cyclic nucleotide elimination.
Research indicates that ABCC5 provides resistance to thiopurine anticancer drugs (6-mercaptopurine, thioguanine) and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. It may play a role in resistance mechanisms in acute lymphoblastic leukemia and HIV-infected patients treated with nucleoside analogs.
Alternative splicing of this gene has been observed, though the complete sequence and translation initiation site remain unclear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific PIAS2 Monoclonal Antibody (OTI5B4), TrueMAB
600,200원
Thermo Fisher Scientific
Thermo Fisher Scientific PRKAB2 Monoclonal Antibody (OTI4H4), TrueMAB
600,200원
Thermo Fisher Scientific
Thermo Fisher Scientific ABCC5 Monoclonal Antibody (OTI1F3), TrueMAB
600,200원
Thermo Fisher Scientific
Thermo Fisher Scientific ABCC5 Monoclonal Antibody (OTI5F4), TrueMAB
600,200원
Thermo Fisher Scientific
Thermo Fisher Scientific WTAP Monoclonal Antibody (OTI2C4), TrueMAB
600,200원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|