Thermo Fisher Scientific CD4 Monoclonal Antibody (CT-4), APC
닭 CD4 항원을 인식하는 단클론 항체로, APC 형광체가 결합되어 유세포분석(Flow Cytometry)에 적합합니다. Mouse IgG1, kappa 아이소타입이며, 4°C 암소 보관이 필요합니다. 다양한 포맷(FITC, PE, Biotin 등)으로도 제공됩니다.
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Applications
- Flow Cytometry (Flow): Tested at 0.1 µg/10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Avian, Chicken |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CT-4 |
| Immunogen | Chicken thymocytes and Ig-negative blood leukocytes |
| Conjugate | APC (Allophycocyanin) |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.5, with proprietary stabilizer |
| Contains | <0.1% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745642 |
Additional Formats
- Unconjugated (MA5-28687)
- Biotin (MA5-28684)
- FITC (MA5-28685)
- PE (MA5-28686)
- Request custom conjugation
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in T helper cells but can also be found in monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression is observed in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut. CD4 participates in early T-cell activation via interaction with the T-cell receptor complex and tyrosine kinase Lck, and may mediate neuronal damage in immune-related CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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