
Thermo Fisher Scientific MRPL11 Monoclonal Antibody (OTI1E5)
MRPL11 단백질을 인식하는 Thermo Fisher Scientific의 Mouse IgG1 단클론 항체로, Western blot 및 IHC(Paraffin)에 적합합니다. 인간 반응성, 비결합형 액상 형태이며 고순도 친화 크로마토그래피 정제 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E5 |
| Immunogen | Full length human recombinant protein of MRPL11 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724731 |
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and assist in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with an estimated 75% protein to rRNA ratio—opposite to that of prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. Proteins comprising the mitoribosome vary significantly among species, complicating recognition by sequence homology. The MRPL11 gene encodes a 39S subunit protein, and sequence analysis identified three transcript variants encoding different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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