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Thermo Fisher Scientific TRMT12 Monoclonal Antibody (OTI8C7), TrueMAB
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Thermo Fisher Scientific TRMT12 Monoclonal Antibody (OTI8C7), TrueMAB

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인간 TRMT12 단백질을 인식하는 Mouse IgG2a 단클론 항체. Western blot에 1:2,000 희석 비율로 검증됨. Affinity chromatography로 정제된 액상 형태이며, PBS/BSA/glycerol buffer에 보관. TRMT12는 tRNA wybutosine 생합성에 관여하며 암 관련 연구에 유용.

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마지막 업데이트 2025. 08. 05. 오전 04:03
Thermo Fisher Scientific TA809550 TRMT12 Monoclonal Antibody (OTI8C7), TrueMAB 100 ul pk판매 단위 pk ·
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600,200원VAT 포함 660,220원

Thermo Fisher Scientific · Thermo Fisher Scientific TRMT12 Monoclonal Antibody (OTI8C7), TrueMAB

Applications

  • Western Blot (WB): Tested dilution 1:2,000

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Clone OTI8C7
Immunogen Full-length human recombinant TRMT12 protein produced in E. coli
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

TYW2, also known as TRMT12, is an enzyme involved in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine adjacent to the anticodon of phenylalanine tRNA, stabilizing codon-anticodon interactions during ribosomal decoding.
TYW2 participates in a multistep enzymatic reaction ensuring accurate translation. It has been reported to be amplified in breast cancer cell lines and overexpressed in breast tumors, suggesting a potential role in oncogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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