Thermo Fisher Scientific Androgen Receptor Recombinant Rabbit Monoclonal Antibody (23GB3210)
Thermo Fisher Scientific의 Androgen Receptor Recombinant Rabbit Monoclonal Antibody (23GB3210)는 인간 및 마우스 시료에서 AR 단백질 검출용으로 최적화된 항체입니다. Western blot, ICC/IF, Flow cytometry에 사용 가능하며, 고순도 액상 형태로 안정적인 결과를 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB3210 |
| Immunogen | A synthetic peptide of human Androgen Receptor (3–65AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The androgen receptor (AR) is a member of the steroid-hormone receptor superfamily of nuclear receptors. It is a ligand-activated transcription factor that binds testosterone (T) and dihydrotestosterone (DHT). Upon ligand binding, the receptor translocates to the nucleus, dimerizes, and activates transcription of androgen-responsive genes. AR signaling is critical for development and function of male reproductive organs and also affects nonreproductive tissues such as muscle, hair follicles, and brain.
AR is a phosphoprotein that regulates MAP kinase signaling, and abnormal AR activity has been linked to prostate cancer, Kennedy’s disease, and male infertility. Mutations in the AR gene are associated with complete androgen insensitivity (CAIS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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