Invitrogen™

PFB-FDGlu (5-(Pentafluorobenzoylamino)Fluorescein Di-β-D-Glucopyranoside)

PFB-FDGlu is a cell-permeable substrate used for live cell imaging of GCase activity. It fluoresces green upon cleavage by lysosomal GCase, facilitating specific, single-cell analysis via high-content imaging, flow cytometry, and microscopy.

PFB-FDGlu (5-(Pentafluorobenzoylamino) Fluorescein Di-beta-D-Glucopyranoside) is a glycosidase activity probe for live cell imaging of lysosomal glucocerebrosidase (GCase) activity. This enzyme is vital for glycolipid metabolism, and its deficiency is linked to diseases like Gauchers and Parkinsons. PFB-FDGlu fluoresces green upon cleavage by GCase, allowing specific, single-cell analysis via flow cytometry, fluorescent microscopy, and high-content imaging.

사양

세포 투과성Cell-Permeant

색상Green

검출 방법Fluorescence

형태Powder

수량5 mg

기질GCase Substrate

Substrate PropertiesChemical Substrate

기질 유형Beta-Glucosidase Substrate

Target EnzymeBeta-Glucosidase

여기/방출492/526

용도(장비)Flow Cytometer, High Content Imaging Instrument, Fluorescent Microscope, Confocal Microscope

라벨 또는 염료Fluorescein

제품 유형Substrate

배송 조건Room Temperature

보관 요구 사항Freezer (-5°C to -30°C)

Unit SizeEach