Thermo Fisher Scientific Calpain 12 Polyclonal Antibody
Calpain 12 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, 인체·마우스·래트 반응성. 연구용 전용 제품.
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Thermo Fisher Scientific Calpain 12 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Calpain 12 (amino acids 201–310) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases functioning as nonlysosomal intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific forms. The ubiquitous enzymes are heterodimers composed of distinct large catalytic subunits and a common small regulatory subunit.
The Calpain 12 gene encodes the large subunit of the ubiquitous enzyme calpain 1. Multiple transcript variants encoding different isoforms have been identified.
Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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