Thermo Fisher Scientific CD162 Monoclonal Antibody (TC2), FITC
CD162(PSGL-1) 인식하는 마우스 모노클로날 항체로 FITC 형광 표지. 인간 시료에 반응하며 유세포분석(Flow Cytometry)에 적합. 4°C 암소 보관, 동결 금지. 면역세포 표지 및 면역학 연구용.
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Applications
- Flow Cytometry (Flow): 20 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TC2 |
| Immunogen | Human thymocytes |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154255 |
Additional Formats
- Unconjugated (MA1-10114)
- APC (MA1-10115)
- PE (MA1-10117)
- Custom conjugation available upon request
Product Specific Information
This antibody reacts with an extracellular epitope of CD162, a 220 kDa type I integral membrane protein expressed as a disulfide-linked homodimer (sialomucin family).
CD162 is present on most peripheral blood T lymphocytes, monocytes, and granulocytes; it is also expressed on a subpopulation of B lymphocytes and CD34⁺ bone marrow cells.
Target Information
CD162 (PSGL-1) is a 120 kDa homodimer protein found on leukocytes and platelets.
It binds CD62P (P-selectin), CD62L (L-selectin), and to a lesser extent CD62E (E-selectin).
These interactions are critical for leukocyte adhesion, rolling, and extravasation.
CD162 is an important immune marker of T cell exhaustion in chronic viral infections and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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