Thermo Fisher Scientific SIRT4 Polyclonal Antibody
Thermo Fisher Scientific SIRT4 Polyclonal Antibody는 인간 SIRT4 단백질을 인식하는 토끼 IgG 기반 항체입니다. Western blot 및 IHC에 사용 가능하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보관하며 연구용으로 적합합니다.
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- PA568562
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- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–1.0 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | Assay-dependent | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human SIRT4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688375 |
Product Specific Information
This target displays homology in the following species:
Cow: 93%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 93%, Rat: 93%, Sheep: 92%
Target Information
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes.
The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.
Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
The protein encoded by this gene is included in class IV of the sirtuin family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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