Thermo Fisher Scientific NAPSA Monoclonal Antibody (OTI9F1), TrueMAB
인체 NAPSA 단백질을 인식하는 Mouse monoclonal 항체로, IHC(P) 및 ICC/IF에 적합합니다. Lung 및 renal 조직 연구에 활용되며, 암종 구분과 바이오마커 분석에 유용합니다. 1 mg/mL 농도의 액상 형태로, -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 64–244 of human NAPSA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Napsin 1 is an aspartic protease generally expressed in the lung and kidney, and in metastatic carcinomas. It processes surfactant protein B in healthy pulmonary and renal tissues but is abnormally regulated during carcinogenesis. Napsin evaluation is useful for identifying several cancers and differentiating primary tumors from metastases. Combined with thyroid transcription factor analysis, Napsin serves as a specific biomarker for carcinoma differentiation. It is also associated with pulmonary alveolar proteinosis and protein catabolism in renal tubules.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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