Thermo Fisher Scientific NDUFS1 Polyclonal Antibody
NDUFS1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 적합하며 인간, 생쥐, 랫드 반응성. 항원 친화 크로마토그래피로 정제, PBS/glycerol buffer에 보존. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 432–664 of NDUFS1 (Uniprot ID: P28331) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.57 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11151879 |
Product Specific Information
- Recommended positive controls: Molt-4, mouse brain, rat brain.
- Predicted reactivity: Mouse (90%), Rat (93%), Zebrafish (82%), Xenopus laevis (85%), Chicken (86%), Chimpanzee (100%), Bovine (96%).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits located at the mitochondrial inner membrane.
This protein has NADH dehydrogenase and oxidoreductase activity, transferring electrons from NADH to the respiratory chain, with ubiquinone as the immediate electron acceptor.
It is the largest subunit of complex I and part of the iron-sulfur fragment, possibly forming part of the active site where NADH is oxidized.
Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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