Thermo Fisher Scientific Cardiac Troponin T Monoclonal Antibody (13-11)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

View 14 publications 14 publications

Immunohistochemistry (IHC)

-

View 76 publications 76 publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

View 5 publications 5 publications

Immunohistochemistry (PFA fixed) (IHC (PFA))

-

View 4 publications 4 publications

Immunohistochemistry (Frozen) (IHC (F))

5 µg/mL

View 4 publications 4 publications

Immunocytochemistry (ICC/IF)

5 µg/mL

View 113 publications 113 publications

Flow Cytometry (Flow)

-

View 60 publications 60 publications

Miscellaneous PubMed (Misc)

-

View 4 publications 4 publications

Product Specifications

Species Reactivity

Avian, Dog, Chicken, Fish, Guinea pig, Human, Mouse, Pig, Rabbit, Rat

Published species

Dog, Fish, Hamster, Human, Mouse, Pig, Rat, Xenopus, Zebrafish

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

13-11

Immunogen

Purified rabbit cardiac troponin T isoform (TnT4R)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 0.2% BSA

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11000742

Product Specific Information

MA5-12960 targets Troponin T Cardiac Isoform in IF/ICC, IHC (P), and IM applications and shows reactivity with Avian, Canine, Chicken, Fish, Guinea Pig, Human, mouse, Porcine, Rabbit, and Rat samples.

The MA5-12960 immunogen is purified rabbit cardiac troponin T isoform (TnT4R).

Target Information

Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.