Thermo Fisher Scientific Phospho-Acetyl-Histone H3 (Lys10, Ser11) Polyclonal Antibody
Phospho-Acetyl-Histone H3 (Lys10, Ser11) 폴리클로날 항체로 인간, 마우스, 랫트 시료에 반응합니다. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. 고순도 Protein A 정제, 안정적인 액상 형태로 연구용에 최적화되어 있습니다.
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Thermo Fisher Scientific Phospho-Acetyl-Histone H3 (Lys10, Ser11) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Acetyl and Histone H3 (Ac-Lys10/p-Ser11) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Modulation of chromatin structure is crucial for transcription regulation in eukaryotes. The nucleosome, composed of four core histone proteins (H2A, H2B, H3, and H4), forms the basic unit of chromatin. The N-terminal tails of these histones undergo various posttranslational modifications such as acetylation, phosphorylation, and methylation, influencing gene expression in response to cellular signals.
Histone H3 is primarily acetylated at lysines 9, 14, 18, and 23, and phosphorylation at Ser10 is closely associated with chromosome condensation during mitosis and meiosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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