Thermo Fisher Scientific Aurora A Polyclonal Antibody
Aurora A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot과 ELISA에 적합합니다. 세포주 HeLa, MCF7, HepG2에서 양성 대조로 사용 가능하며, 세포 분열 관련 단백질 연구에 활용됩니다.
- 카탈로그번호
- PA5120390
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–130 of human AURKA (NP_940837.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.01 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913962 |
Product Specific Information
- Positive test controls: HeLa, MCF7, HepG2
- Target localization: Cytoplasm, centriole, centrosome, cilium basal body, cytoskeleton, microtubule organizing center, spindle pole
Immunogen sequence:
MDRSKENCIS GPVKATAPVG GPKRVLVTQQ FPCQNPLPVN SGQAQRVLCP SNSSQRIPLQ AQKLVSSHKP VQNQKQKQLQ ATSVPHPVSR PLNNTQKSKQ PLPSAPENNP EEELASKQKN EESKKRQWAL
Target Information
AURKA (Aurora A) is a serine/threonine kinase that regulates mitosis by association with centrosomes. Overexpression of AURKA is observed in many cancer types. Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, contributing to chromosome segregation at the centrosome/spindle pole region. It is highly expressed in testis and weakly in skeletal muscle, thymus, and spleen. Aurora A is considered a potential target for anticancer drug development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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