Thermo Fisher Scientific CAD Polyclonal Antibody
Thermo Fisher Scientific의 CAD Polyclonal Antibody는 인간, 생쥐, 랫트 시료에 반응하는 Rabbit IgG 기반 항체로, WB, IHC, ICC/IF, ELISA 등에 적합합니다. 고순도 Affinity Chromatography 정제 제품으로, 안정적인 액상 형태로 제공됩니다.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1650–1900 of human CAD (NP_0043322) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.36 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2808817 |
Product Specific Information
Immunogen sequence:
LERLGPGKGE VRPELGSRQD VEALWENMAV IDCFASDHAP HTLEEKCGSR PPPGFPGLET MLPLLLTAVS EGRLSLDDLL QRLHHNPRRI FHLPPQEDTY VEVDLEHEWT IPSHMPFSKA HWTPFEGQKV KGTVRRVVLR GEVAYIDGQV LVPPGYGQDV RKWPQGAVPQ LPPSAPATSE MTTTPERPRR GIPGLPDGRF HLPPRIHRAS DPGLPAEEPK EKSSRKVAEP ELMGTPDGTC YPPPPVPRQA S
Positive Samples: SW620, HepG2, HeLa, HL-60
Cellular Location: Cytoplasm, Nucleus
Target Information
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein associated with the enzymatic activities of the first three enzymes in the six-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, indicating a direct link between MAPK activation and de novo pyrimidine nucleotide biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-97015_CAD_P27708-1_Rabbit.svg)
(이미지: PA5-97015_CAD_P27708-1_Rabbit_PDP.jpeg)
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