Thermo Fisher Scientific Neuritin Polyclonal Antibody
Neuritin 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 적합합니다. 사람, 마우스, 랫트 시료에 반응하며, 동결건조 형태로 제공됩니다. 신경세포 분화 및 신경가소성 연구에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 40–80 of human Neuritin conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C (short term). For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Neuritin.
Target Information
Neuritin belongs to the neuritin family and is expressed in postmitotic-differentiating neurons of the developing nervous system as well as neuronal structures associated with plasticity in adults. Its expression can be induced by neural activity and neurotrophins. The protein contains a consensus cleavage signal typical of glycosylphosphatidylinositol (GPI)-anchored proteins and promotes neurite outgrowth and arborization, indicating its role in promoting neuritogenesis. Overexpression may be associated with astrocytoma progression. Alternative splicing leads to multiple transcript variants. NRN1 is associated with Severe Congenital Neutropenia 8 and Spinal Muscular Atrophy, Type III.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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