Thermo Fisher Scientific ZNF268 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ZNF268 (NP_0011593531) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZNF268,uniProtId:Q14587-1,ncbiNodeId:9606,antigenRange:1-270,antigenLength:947,antigenImageFileName:PA5-88851_ZNF268_Q14587-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88851_ZNF268_Q14587-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.28 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805171

Product Specific Information

Immunogen sequence: MATRVRTASI WVPPLQERNS SWDRIRKLQG QESILGQGTP GLQPLPGTPR QKQKSRRIEK VLEWLFISQE QPKITKSWGP LSFMDVFVDF TWEEWQLLDP AQKCLYRSVM LENYSNLVSL GYQHTKPDII FKLEQGEELC MVQAQVPNQT CPNTVWKIDD LMDWHQENKD KLGSTAKSFE CTTFGKLCLL STKYLSRQKP HKCGTHGKSL KYIDFTSDYA RNNPNGFQVH GKSFFHSKHE QTVIGIKYCE SIESGKTVNK KSQLMCQQMY; Positive Samples: Mouse kidney, Rat ovary; Cellular Location: Cytoplasm, Nucleus, Nucleus

Target Information

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 268 (ZNF268), also known as zinc finger protein 3 or HZF3, is a 947 amino acid protein belonging to the krueppel C2H2-type zinc-finger protein family. ZNF268 contains 24 C2H2-type zinc fingers and one KRAB domain. Localized to the nucleus, ZNF268 is involved in transcriptional regulation and is highly expressed in three to five week old embryos. ZNF268 has been implicated in human leukemia, due to the identification of an alternatively spliced form in leukemia patients. Two named isoforms of ZNF268 exist as a result of alternative splicing events.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.