Thermo Fisher Scientific ZNF268 Polyclonal Antibody
ZNF268 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 핵 및 세포질 내 ZNF268 발현 연구에 활용됩니다. Affinity Chromatography로 정제된 고품질 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 1–270 of human ZNF268 (NP_001159353.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.28 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805171 |
Product Specific Information
- Immunogen sequence:
MATRVRTASI WVPPLQERNS SWDRIRKLQG QESILGQGTP GLQPLPGTPR QKQKSRRIEK VLEWLFISQE QPKITKSWGP LSFMDVFVDF TWEEWQLLDP AQKCLYRSVM LENYSNLVSL GYQHTKPDII FKLEQGEELC MVQAQVPNQT CPNTVWKIDD LMDWHQENKD KLGSTAKSFE CTTFGKLCLL STKYLSRQKP HKCGTHGKSL KYIDFTSDYA RNNPNGFQVH GKSFFHSKHE QTVIGIKYCE SIESGKTVNK KSQLMCQQMY - Positive Samples: Mouse kidney, Rat ovary
- Cellular Location: Cytoplasm, Nucleus
Target Information
Zinc-finger proteins contain DNA-binding domains and play diverse roles in transcriptional activation or repression. Most zinc-finger proteins possess a Krueppel-type DNA-binding domain and a KRAB domain that interacts with KAP1, recruiting histone-modifying proteins.
ZNF268 (Zinc finger protein 268), also known as zinc finger protein 3 or HZF3, is a 947-amino-acid protein of the Krueppel C2H2-type zinc-finger family. It contains 24 C2H2-type zinc fingers and one KRAB domain. Localized to the nucleus, ZNF268 participates in transcriptional regulation and is highly expressed in early embryonic development. Alternative splicing variants have been identified in leukemia patients, suggesting a role in oncogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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