Thermo Fisher Scientific NBN Monoclonal Antibody (OTI2G4), TrueMAB
인간 NBN 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P) 검증 완료. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 버퍼에 보존. 연구용으로 DNA 손상 복구 및 세포주기 조절 연구에 적합.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 183–460 of human NBN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This complex is implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity. It reveals a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: TA801390_NBS1_O60934-1_House_mouse.svg, TA801390_NBS1_O60934-1_House_mouse_PDP.jpeg)
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