Thermo Fisher Scientific RSK1 Polyclonal Antibody
RSK1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA 등에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 600 to the C-terminus of human p90Rsk/RSK1/RPS6KA1 (NP_0029442) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.99 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806160 |
Product Specific Information
- Immunogen sequence:
LGILLYTMLA GYTPFANGPS DTPEEILTRI GSGKFTLSGG NWNTVSETAK DLVSKMLHVD PHQRLTAKQV LQHPWVTQKD KLPQSQLSHQ DLQLVKGAMA ATYSALNSSK PTPQLKPIES SILAQRRVRK LPSTTL - Positive Samples: HT-29, HeLa, MCF7, K-562, Mouse lung, Mouse brain
- Cellular Location: Cytoplasm, Nucleus
Target Information
RPS6KA1 (RSK1) is a growth-factor regulated serine/threonine kinase involved in the MAPK cascade. It regulates cellular proliferation and differentiation through phosphorylation of transcription factors. RPS6KA1 has two nonidentical kinase catalytic domains and phosphorylates substrates in the MAPK signaling pathway. Its activity is implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants encoding different isoforms have been characterized.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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