
ELK Biotechnology DMBT1 rabbit pAb
DMBT1 단백질을 인식하는 토끼 폴리클로날 항체로, IHC 및 IF 실험에 적합합니다. 인간, 마우스, 랫트에서 반응하며 265kD 밴드를 검출합니다. 합성 펩타이드로 면역화되었으며 -20°C에서 1년 보관 가능합니다.
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제품 개요
제품명: DMBT1 rabbit pAb
공급업체: ELK Biotechnology
DMBT1 단백질에 특이적인 토끼 폴리클로날 항체입니다. IHC 및 IF 실험에서 사용 가능하며, 인간, 마우스, 랫트 시료에서 반응합니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Product name | DMBT1 rabbit pAb |
| Applications | IHC; IF |
| Recommended Dilutions | IHC-p 1:50–300 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 265 kD |
| GeneID (Human) | 1755 |
| Human Swiss-Prot No | Q9UGM3 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Secreted. Some isoforms may be membrane-bound. Localized to the lumenal aspect of crypt cells in the small intestine and surface epithelial cells in the colon. Also formed in ducts of von Ebner gland and released into the fluid bathing the taste buds (By similarity). |
Background
Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. It is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) binds surfactant protein D independently of carbohydrate recognition, suggesting that DMBT1 may play a role in tumor–immune system interactions rather than acting as a classical tumor suppressor gene.
(RefSeq, Mar 2016)
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