ELK Biotechnology LCAP rabbit pAb

제품명

LCAP rabbit pAb

공급업체

ELK Biotechnology

제품 설명

LCAP rabbit pAb는 인간 단백질의 특정 영역(AA 705–755)에서 유래한 합성 펩타이드를 면역원으로 사용한 다클론 항체입니다. WB 및 ELISA 실험에 적합하며, 세포막 및 분비형 단백질 검출에 활용됩니다.

응용 분야

• WB (Western Blot)
• ELISA

권장 희석 배수

• WB: 1:500–2000
• ELISA: 1:5000–20000

스펙 정보

세포 내 위치

Cell membrane; Single-pass type II membrane protein. In brain, only the membrane-bound form is found. The protein resides in intracellular vesicles together with GLUT4 and can translocate to the cell surface in response to insulin and/or oxytocin. Localization may be determined by dileucine internalization motifs and/or by interaction with tankyrases.
[Leucyl-cystinyl aminopeptidase, pregnancy serum form]: Secreted. During pregnancy, serum levels are low in the first trimester, rise progressively during the second and third trimester, and decrease rapidly after parturition.

유전자 배경 정보

This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A, and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. It catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and acts as a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]