ELK Biotechnology TBA1A rabbit pAb
ELK Biotechnology의 TBA1A rabbit pAb는 인간, 생쥐, 랫트 시료에서 알파 튜불린 단백질을 검출하는 폴리클로날 항체입니다. WB와 ELISA에 사용 가능하며, 높은 특이성과 안정성을 제공합니다. 세포골격 연구 및 신경세포 분화 관련 연구에 적합합니다.
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제품명
TBA1A rabbit pAb
제품 개요
ELK Biotechnology에서 제공하는 TBA1A rabbit polyclonal antibody는 인간, 생쥐, 랫트 시료에서 알파 튜불린 단백질을 검출하기 위한 항체입니다. 세포골격 및 미세소관 관련 연구에 활용됩니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000 / ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein (AA range: 348–398) |
| Species Reactivity | Human; Rat; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 49 kD |
| Gene ID (Human) | 7846 |
| Human Swiss-Prot No | Q71U36 |
| Cellular Localization | Cytoplasm, cytoskeleton |
| Storage | -20°C (1 year) |
| Source | Rabbit |
Background
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes.
The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.
This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
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