ELK Biotechnology NPY6R rabbit pAb
Human과 Mouse에 반응하는 NPY6R rabbit polyclonal antibody로 WB 및 ELISA에 적합. 합성 펩타이드 면역원 사용, 막 단백질 검출에 유용. 고농도(1 mg/ml)로 안정적이며 -20°C에서 1년 보관 가능.
- 판매단위
- pk
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제품명
NPY6R rabbit pAb
적용 분야
- Western Blot (WB)
- ELISA
권장 희석 배수
- WB: 1:500–1:2000
- ELISA: 1:5000–1:20000
제품 정보
| 항목 | 내용 |
|---|---|
| Immunogen | Synthesized peptide derived from human protein (AA range: 190–270) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 31 kD |
| Human Swiss-Prot No | Q99463 |
| Cellular Localization | Membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse |
| Storage | -20°C / 1 year |
Background
Caution: Could be the product of a pseudogene. According to PubMed:97066888, PubMed:97066971, and PubMed:9013614, the human NPY6R gene is an expressed pseudogene containing a premature stop codon and encoding a non-functional truncated protein missing the last transmembrane domain.
A single base pair deletion relative to the mouse ortholog results in a truncated protein lacking the seventh transmembrane domain.
When expressed, it is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function.
Belongs to the G-protein coupled receptor 1 family.
Expressed in heart, skeletal muscle, gastrointestinal tissues, spleen, brain, and adrenal glands.
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