ELK Biotechnology T2R38 rabbit pAb
T2R38 단백질을 인식하는 토끼 다클론 항체로, WB 및 ELISA에 사용 가능. 인간, 랫드, 마우스 반응성. 막단백질 검출에 적합하며, -20°C에서 1년 보관 가능. 농도 1 mg/ml, IgG 아이소타입.
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제품명
T2R38 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 180–260) |
| Species Reactivity | Human; Rat; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 36 kD |
| Gene ID (Human) | 5726 |
| Human Swiss-Prot No | P59533 |
| Cellular Localization | Membrane; Multi-pass membrane protein |
| Storage | -20°C, 1 year |
Background
This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica species. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, two predominant common forms (taster and non-taster) are found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes (A49P, A262V, and V296I), with the amino acid combination PAV identifying the taster variant and AVI identifying the non-taster variant. [provided by RefSeq, Oct 2009]
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