ELK Biotechnology GNRR2 rabbit pAb
GNRR2 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 ELISA에 적합합니다. 인간, 쥐, 생쥐 시료에 반응하며 세포막 단백질 검출에 유용합니다. 고순도 IgG 형태로 -20°C에서 1년 보관 가능합니다.
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ELK Biotechnology GNRR2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | GNRR2 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 10–90) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 32 kDa |
| Human Swiss-Prot No | Q96P88 |
| Cellular localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
In non-hominoid primates and non-mammalian vertebrates, the gonadotropin releasing hormone 2 receptor gene (GnRHR2) encodes a seven-transmembrane G-protein coupled receptor. However, in humans, the corresponding reading frame contains a premature stop codon, which has been suggested to encode a selenocysteine residue, but there is no solid evidence for selenocysteine incorporation (PMID: 12538601). It appears that human GnRHR2 transcription occurs, but the gene does not likely produce a functional multi-transmembrane protein. A non-transcribed pseudogene of GnRHR2 is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2013]
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