ELK Biotechnology C5ARL rabbit pAb
C5ARL rabbit polyclonal antibody for WB and ELISA applications. Targets human C5ARL protein involved in complement system signaling. High specificity and stability with long-term storage at -20°C. Suitable for research on immune response and disease me...
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C5ARL rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 270–350) |
| Species Reactivity | Human; Rat; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 37 kD |
| GeneID (Human) | 27202 |
| Human Swiss-Prot No | Q9P296 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Storage | -20°C / 1 year |
| Source Host | Rabbit |
Background
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. (Provided by RefSeq, Nov 2012)
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