
ELK Biotechnology CCR8 rabbit pAb
CCR8 rabbit pAb는 인간 및 마우스 시료에 반응하는 폴리클로날 항체로, WB와 ELISA에 적합합니다. 세포막 단백질 검출에 사용되며, 높은 특이성과 재현성을 제공합니다. 장기 보관이 가능한 -20°C 조건에서 안정적입니다.
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제품명
CCR8 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 250–330) |
| Host Species | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 39 kD |
| Gene ID (Human) | 1237 |
| Human Swiss-Prot No. | P51685 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse |
배경 (Background)
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into inflammatory sites. This receptor protein is preferentially expressed in the thymus. I-309, thymus activation-regulated cytokine (TARC), and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggest its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]
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