ELK Biotechnology GNAS3 rabbit pAb
GNAS3 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 사람, 랫드, 마우스 시료에 반응하며, 26kDa 밴드를 검출합니다. 합성 펩타이드 면역원으로 제작되었으며, -20°C에서 1년 보관 가능합니다.
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GNAS3 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | GNAS3 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 171–220) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 26 kDa |
| Gene ID (Human) | 2778 |
| Human Swiss-Prot No. | O95467 |
| Cellular Localization | Cytoplasmic vesicle, secretory vesicle, secreted, neuroendocrine secretory granules |
| Species Reactivity | Human; Rat; Mouse |
Background
This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts derived from four alternative promoters and 5′ exons. Some transcripts contain a differentially methylated region (DMR) at their 5′ exons, commonly found in imprinted genes and correlated with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts and the antisense transcript are paternally expressed noncoding RNAs that may regulate imprinting in this region. Additionally, one transcript contains a second overlapping ORF encoding a structurally unrelated protein (Alex). Alternative splicing of downstream exons results in different forms of the stimulatory G-protein alpha subunit, a key regulatory molecule.
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