ELK Biotechnology CGB1 rabbit pAb
CGB1 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 인간, 랫드, 마우스 시료에 반응하며, 고순도의 IgG 형식으로 제공됩니다. -20°C에서 1년간 보관 가능합니다.
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ELK Biotechnology CGB1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CGB1 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: Internal) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 20 kD |
| GeneID (Human) | 114335 |
| Human Swiss-Prot No. | A6NKQ9 |
| Cellular localization | Secreted |
| Species Reactivity | Human; Rat; Mouse |
Background
The beta subunit of chorionic gonadotropin (CGB) is encoded by six highly homologous and structurally similar genes arranged in tandem and inverted pairs on chromosome 19q13.3, contiguous with the luteinizing hormone beta (LHB) subunit gene. The CGB genes are primarily distinguished by differences in the 5′ untranscribed region.
This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of the CGB subunit. However, detection of CGB1 and CGB2 transcripts in vivo, and their presence on polysomes, suggested that these transcripts are translated. To date, a protein product corresponding to CGB1 has not been isolated. The deduced sequence of the hypothetical protein of 132 amino acids does not share similarity with functional CGB subunits (PMID:8954017). However, a 155 amino acid protein translated from a different frame is about the same size and shares structural features.
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