Thermo Fisher Scientific CD4 (T-Helper/Inducer Cell Marker) Monoclonal Antibody (CD4/1604)
인간 CD4 항원을 인식하는 Mouse IgG2b 단클론 항체로, Flow Cytometry 및 ELISA에 사용 가능. HIV 연구 및 T-helper 세포 표지에 적합. 단백질 A/G 정제, PBS 용액 형태, 보존제 없음. 연구용으로만 사용.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CD4/1604 |
| Immunogen | Recombinant human CD4 protein fragment (around aa 245–392) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and serves as a co-receptor for HIV. CD4 is primarily expressed in T-helper lymphocytes but can also be found in monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression is observed in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut. CD4 aids in early T-cell activation through association with the T-cell receptor complex and protein tyrosine kinase Lck, and may contribute to neuronal damage in infectious and immune-mediated CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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