Thermo Fisher Scientific PLCD3 Polyclonal Antibody
인간 PLCD3 단백질에 특이적인 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에서 검증됨. 항원 친화 크로마토그래피로 정제된 액상 형태. 4°C 단기 보관, -20°C 장기 보관 권장.
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- PA584166
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PLCD3. Recombinant protein control fragment (Product #RP-108399). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791318 |
Product Specific Information
Immunogen sequence:
EGHQSEGLRR FGGAFAPARC LTIAFKGRRK NLDLAAPTAE EAQRWVRGLT KLRARLDAMS QRERLDHWIH SYLHRADSNQ DSKMSFKEIK SLLRMVNVDM NDMYAYLLFK
Target Information
This gene encodes a member of the phospholipase C family, which catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3).
Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca²⁺ concentrations.
This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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