Thermo Fisher Scientific PLCD3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PLCD3. Recombinant protein control fragment (Product #RP-108399). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PLCD3,uniProtId:Q8N3E9-1,ncbiNodeId:9606,antigenRange:119-228,antigenLength:789,antigenImageFileName:PA5-84166_PLCD3_Q8N3E9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-84166_PLCD3_Q8N3E9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2791318

Product Specific Information

Immunogen sequence: EGHQSEGLRR FGGAFAPARC LTIAFKGRRK NLDLAAPTAE EAQRWVRGLT KLRARLDAMS QRERLDHWIH SYLHRADSNQ DSKMSFKEIK SLLRMVNVDM NDMYAYLLFK

Target Information

This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to generate the second messengers diacylglycerol and inositol 1, 4, 5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.