
Thermo Fisher Scientific ACP6 Polyclonal Antibody
Thermo Fisher Scientific의 ACP6 Polyclonal Antibody는 인간 ACP6 단백질을 인식하는 토끼 다클론 항체입니다. Western blot 및 IHC(P) 분석에 적합하며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ACP6. Recombinant protein control fragment (Product # RP-94413) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2637612 |
Product Specific Information
Immunogen sequence:
SLQPGISEDL KKVKDRMGID SSDKVDFFIL LDNVAAEQAH NLPSCPMLKR FARMIEQRAV DTSLYILPKE DRESLQMAV
Highest antigen sequence identity to orthologs:
- Mouse: 67%
- Rat: 68%
Target Information
Lysophosphatidic acid phosphatase type 6 (ACP6), also known as acid phosphatase-like protein 1 (ACPL1) or lysophosphatidic acid phosphatase (LPAP), is a 428 amino acid secreted protein that hydrolyzes lysophosphatidic acid to monoacylglycerol.
ACP6 is highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, and ovary. It exists as two isoforms resulting from alternative splicing.
The ACP6 gene is located on human chromosome 1, which spans about 260 million base pairs and constitutes approximately 8% of the human genome. Chromosome 1 is associated with several diseases such as Hutchinson-Gilford progeria (LMNA gene), Stickler syndrome, Parkinson’s disease, Gaucher disease, familial adenomatous polyposis, and Usher syndrome. Aberrations in chromosome 1 are found in various cancers including head and neck cancer, malignant melanoma, and multiple myeloma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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