Thermo Fisher Scientific MCM3 Recombinant Rabbit Monoclonal Antibody (23GB2490)
MCM3 단백질을 표적으로 하는 토끼 유래 재조합 단클론 항체로, Western blot 및 면역세포염색(ICC/IF)에 적합합니다. HEK293F 시스템에서 발현되었으며, 고순도의 Affinity chromatography로 정제되었습니다. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB2490 |
| Immunogen | A synthesized peptide derived from human HLTF (1–44 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and recruitment of other DNA replication-related proteins.
This protein is a subunit of the MCM2–7 complex and interacts directly with MCM5/CDC46. It also interacts with, and is acetylated by, MCM3AP, a chromatin-associated acetyltransferase. Acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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