Thermo Fisher Scientific BPNT1 Polyclonal Antibody
BPNT1 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체입니다. Western blot에 적합하며 인간 반응성을 확인하였고, 마우스 및 랫드에서도 예측 반응성을 보입니다. 액상형, 비결합 항체로 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (RNYDYYASRVPESIK) corresponding to the C-terminus amino acids of BPNT1 (aa 289–304) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10982274 |
Product Specific Information
- Predicted to react with mouse and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
BPNT1, also called bisphosphate 3-prime-nucleotidase or BPntase, is a member of the magnesium-dependent phosphomonoesterase family.
Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase.
The predicted human protein is 92% identical to mouse BPntase.
BPntase’s physiological role in nucleotide metabolism may be regulated by inositol signaling pathways.
Inhibition of human BPntase may account for lithium-induced nephrotoxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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