Thermo Fisher Scientific ATP6V0C Polyclonal Antibody
Thermo Fisher Scientific의 ATP6V0C Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 WB, ICC/IF, ELISA에 적합합니다. Rabbit IgG 폴리클로날 항체로, 고순도 친화 크로마토그래피 정제 및 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human ATP6V0C (NP_001185498.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 6.23 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901307 |
Product Specific Information
- Positive Samples: Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Rat liver
- Immunogen sequence: SGTGIAAMSV MRPE
Target Information
ATP6V0C is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for intracellular processes such as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.
V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits, and contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c’, c”, and d. ATP6V0C encodes the V0 subunit c.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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