Thermo Fisher Scientific IL17RD Polyclonal Antibody
IL17RD 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 ELISA에 적합합니다. 인간, 생쥐, 랫트 시료에서 반응하며, 세포막 및 세포질 단백질 검출에 유용합니다. 고순도 Affinity Chromatography 정제 제품으로 연구용으로만 사용됩니다.
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- PA5120067
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Thermo Fisher Scientific IL17RD Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 150–300 of human IL17RD (NP_060033.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.21 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913639 |
Product Specific Information
Positive test controls include: 293T, HT-29, U-87MG, Mouse brain, Mouse kidney, Mouse lung, Rat brain.
The target is usually found in the following locations:
- Cell membrane
- Cytoplasm
- Golgi apparatus membrane
- Single-pass type I membrane protein
Immunogen sequence:
FLNMKFETDY FVKVVPFPSI KNESNYHPFF FRTRACDLLL QPDNLACKPF WKPRNLNISQ HGSDMQVSFD HAPHNFGFRF FYLHYKLKHE GPFKRKTCKQ EQTTETTSCL LQNVSPGDYI IELVDDTNTT RKVMHYALKP VHSPWAGPIR A
Target Information
Feedback inhibitor of fibroblast growth factor-mediated Ras-MAPK signaling and ERK activation.
May inhibit FGF-induced FGFR1 tyrosine phosphorylation.
Regulates the nuclear ERK signaling pathway by blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation.
Mediates JNK activation and may be involved in apoptosis.
Might have a role in early stages of fate specification of GnRH-secreting neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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