Thermo Fisher Scientific IL17RD Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 150-300 of human IL17RD (NP_060033.3). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL17RD,uniProtId:Q8NFM7-1,ncbiNodeId:9606,antigenRange:150-300,antigenLength:739,antigenImageFileName:PA5-120067_IL17RD_Q8NFM7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120067_IL17RD_Q8NFM7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.21 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913639

Product Specific Information

Positive test controls include: 293T, HT-29, U-87MG, Mouse brain, Mouse kidney, Mouse lung, Rat brain. The target is usually found in the following locations: Cell membrane, Cytoplasm, Golgi apparatus membrane, Single-pass type I membrane protein, Single-pass type I membrane protein.

Immunogen sequence: FLNMKFETDY FVKVVPFPSI KNESNYHPFF FRTRACDLLL QPDNLACKPF WKPRNLNISQ HGSDMQVSFD HAPHNFGFRF FYLHYKLKHE GPFKRKTCKQ EQTTETTSCL LQNVSPGDYI IELVDDTNTT RKVMHYALKP VHSPWAGPIR A

Target Information

Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.