Thermo Fisher Scientific Flt3/CD135 Monoclonal Antibody (FLT3/2458)
FLT3/CD135 단일클론 항체로 인간 FLT3 단백질을 표적으로 함. IHC(P) 및 IHC(PFA) 실험에 적합하며 단백질 A/G로 정제된 액상 형태. 연구용으로만 사용되며 세포 증식 및 분화 관련 신호 경로 연구에 유용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FLT3/2458 |
| Immunogen | Recombinant full-length human FLT3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
FLT3 (Fms-like tyrosine kinase 3) is a receptor tyrosine kinase that belongs to the growth factor receptor family. Activation occurs through ligand binding, inducing receptor dimerization and autophosphorylation. This process triggers downstream signaling pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Constitutive activation mutations are associated with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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