Thermo Fisher Scientific NMNAT1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NMNAT1 (residues 229–279). Validated for WB, IHC, IHC-P, and IP applications. Supplied as unconjugated liquid form at 1 mg/mL concentration. Recommended storage at 4°C. For research use only.
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Thermo Fisher Scientific NMNAT1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 229–279 of human Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and Ca²⁺ signaling pathways.
NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).
Publication Note: This RefSeq record includes a subset of available publications. Please see the Entrez Gene record for additional references.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: A304-317A-M_NMNAT1_Q9HAN9-1_Rabbit.svg, A304-317A-M_NMNAT1_Q9HAN9-1_Rabbit_PDP.jpeg)
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